What to expect: The Safety Harbor Resort and Spa is located on the tranquil shores of Tampa Bay. The waterfront resort was built in 1945 on natural mineral springs, and discovered by Spanish explorers searching for the fountain of youth. Designated a Florida Heritage Landmark, this secluded property has been known to business and leisure travelers as a place “where healing waters flow” for the therapeutic value of its waters.

Amenity highlights: The hotel's fitness center features cardio and weight training studios, fitness evaluations, and Tai Chi, Pilates, yoga, and water fitness classes. Two outdoor and one indoor pool are filled with the natural mineral spring water. The Tennis Academy offers individual and group lessons on seven Har-Tru courts. 105 North Restaurant features Caribbean-inspired dishes, and outdoor patio dining and seasonal entertainment add to the resort's ambience.

Insider tip: This resort spa was built over mineral springs discovered in 1539 by Spanish explorer Hernando de Soto. The waters have been coveted for their therapeutic value since the early 1900s and continue to be the source of refreshment and rejuvenation in the resort pools, spa treatments, and drinking water.